Stephen Gilbert, Rho Inc.

Abstract

Bayesian adaptive designs for clinical trials have received increasingly more attention in recent years. Despite a growing body of literature they are however, still relatively rare outside of certain academic centers and present many interesting challenges when used in practice. This talk provides an introduction to some designs used in pharmaceutical research and focuses on their implementation in the non-academic world. We also ask if they are truly Bayesian and if they offer any advantages over frequentist adapative designs.

Location

Room GC,01103,

Roscoe Brady Lecture Hall (located on the 1st floor)

The lecture will start promptly at 3pm.

A Coffee,Tea and Pastry Reception is to follow the talk.

Directions to Genzyme Center

• From the "T" (Recommended)
  

Take the Red Line to the Kendall Square stop. When you exit the station, you will be on Main Street. Walk East - towards Boston - and you will see a traffic light at the corner of Broadway and Third Street. Cross at the intersection and walk down Third Street. Take your first right onto Kendall Street. Genzyme Center is the first building on the left.

• From the Expressway North/South

Take the exit for Storrow Drive. Follow Storrow Drive to the Kendall Square/Government Center exit, and follow the signs for Kendall Square, which will send you across the Longfellow Bridge and into Cambridge. After crossing the river, take a right at the first set of lights onto Third Street. Turn right onto Kendall Street. The parking garage is on your right.
From the Massachusetts Turnpike (I-90 Eastbound)
Take the Mass Turnpike East. Take Exit 18 (Allston/Cambridge). Follow signs toward Cambridge/Somerville. The Doubletree Guest Suites Hotel will be on your right. At the traffic light take a right onto Storrow Drive. Do not cross the river. Take the Kendall Square/Government Center exit off Storrow Drive. Follow the signs for Kendall Square, bearing left around the rotary and across the Longfellow Bridge into Cambridge. After crossing the river, take a right at the first set of lights onto Third Street. Turn right onto Kendall Street. The parking garage is on your right.

http://www.pilgrimparking.com/facilities/kendall_sq/index.php 
 
Prices are as listed, there is no discount for validation. 

• From Logan Airport

Leave your terminal and follow the EXIT signs. Once you are away from the terminal buildings and on the exit road, get into the middle lanes. The left lane will exit for the Mass Transit T Station. You will follow signs for Route 93. Take the next left hand exit for Route 93 and the Sumner Tunnel. Stay to the left, pay $2.00 toll, continue in left lane for Route 93 North. At end of the tunnel go up the ramp for Route 93 North. Stay in the right lane, you'll exit soon. Take Exit 26 Storrow Drive/Somerville/Cambridge. This is a long exit ramp that ends in merging with traffic on the right. Get into the right lane. Take the exit for Causeway Street/Cambridge. At the light take a left, getting in the right-hand lane. Go under the overpass and take a right, passing the Museum of Science. At the first working light, take a left and you will see signs for Kendall Square. At the second light take a right onto Binney Street. At the second light, take a left onto Third Street. Turn left onto Kendall Street. The parking garage is on your right.

To register by check, include the check made payable to BCASA, your name, affiliation, and mail by April 10 to:

Huichao Chen, PhD
Department of Biostatistics/CBAR
Harvard University
651 Huntington Ave, FXB502
Boston, MA 02115